SARMs, short for selective androgen receptor modulators, are a new form of research chemical that thousands of bodybuilders across the world are using.
They have a number of benefits, including:
- Promote Lean Muscle Growth
- Enhance Athletic Performance
- Increase Strength Gains
- Encourage Fat Loss
Many athletes have been using them as of late, and they’ve been a recent topic of much discussion. Just what are these selective androgen receptor modulators, how do they work, and what results can you expect from them, though?
What Are SARMs?
As we published previously here on Guidelines Health, SARMs are supplements that enhance the levels of androgens, or male hormones, in the user’s body.
They do this by binding to androgen receptors, which then signals your body to start building more muscle, while also signaling it to start shredding fat.
SARMs were originally developed in the 1900’s as a way to help cancer patients suffering from muscle loss cope. They were quickly shelved however, until research resumed in the 1990’s.
After ample testing and clinical research, Ligand Pharmaceuticals launched one of the first versions of SARMS that we now know as LGD-4033, or Ligandrol for short.
Since then, users have gotten incredible results from SARMs like Ligandrol, Ostarine, Testolone, and more. Now, let’s take a moment to look at the results you can expect to get, too.
SARMs Results to Expect
When using SARMs, many users can expect to gain up to 30 pounds of muscle in just several months. This amount will change however, depending on how experienced you are.
If you’ve been lifting weights and studying nutrition for a long time, the results you’ll get from your cycle will be quite astounding, and probably similar to the picture above.
In fact, the Ostarine before and after article that Jon Anthony posted on his blog, Masculine Development, are probably some of the best results that you can expect from a cycle.
He says that he gained 21 pounds of muscle and lost 12 pounds of fat, by following a simple beginner’s SARMs cycle of Ostarine, LGD 4033 and Cardarine.
Not everyone will get these results, but the more that you learn about health and fitness, the better the results you’ll get from your cycle.
What Are the Best SARMs?
The best SARM for you will vary depending on your individual needs. Each one of these research chemicals has different effects, strengths, and weaknesses.
RAD 140, or Testolone, for example, is easily the best SARM for building muscle and increasing overall strength. Ostarine, or MK-2866, comes in at a close second.
For shredding fat, Ligandrol and Cardarine are supreme. They selectively target certain androgen receptors that will help you burn fat, while avoiding common side effects.
If you’re looking for a SARMs stack, many users experience great results while stacking a moderate dosage of RAD 140 and Ostarine together, for 90 days.
As a general guideline, here are the maximum dosages for each SARM:
- Ostarine: 50mg/day Maximum Dosage
- Testolone: 30mg/day Maximum Dosage
- MK-677: 25mg/day Maximum Dosage
- Ligandrol: 20mg/day Maximum Dosage
- Cardarine: 20mg/day Maximum Dosage
- YK-11: 10mg/day maximum Dosage
You probably don’t want to take anymore than these dosages however, as they haven’t been proven to be safe. More research still needs to be done on the maximum human dosages.
Common Side Effects
After seeing that SARMs can give users such incredible benefits, most people always ask the question: “Do they have any serious side effects?”
Unfortunately, we’re not quite sure what the long-term side effects are just yet, but we do know that there are very few, if any, short-term side effects, depending on the SARM.
One research paper, conducted at the Boston University School of Medicine, spoke very highly of SARMs, saying that they can enhance athletic performance with very few side effects:
“The last decade has witnessed unprecedented discovery effort to develop selective androgen receptor modulators (SARMs) that improve physical function and bone health without adversely affecting the prostate and cardiovascular outcomes.”
They also state that SARMs “hold promise as a new class of function promoting anabolic therapies,” that can help with aging, chronic disease, frailty, and osteoporosis.
To contrast this, however, Men’s Health recently posted an article claiming that bodybuilding supplements “known as SARMs” actually aren’t as safe as you might think:
“SARMs may actually produce side effects like steroids, says Dr. Bhasin. In addition to the risks above, the side effects of steroids include infertility and mental health problems like depression, aggression, or thoughts of suicide.”
While many users have tried SARMs like Ostarine thus far, and have claimed to experience no side effects, much of this depends on the source you get them from.
The Final Verdict
Overall, we cannot recommend the use of selective androgen receptor modulators. Much more research is needed to determine the long-term and intermediate-term side effects.
The Food and Drug Administration (FDA) also recommends against using them, saying that they’re “extremely concerned” about shady companies selling potentially fake SARMs.
If you do decide to use SARMs, be sure to consult with a licensed medical practitioner. Only you and your doctor can make wise decisions regarding your health, we know this for sure.