What are the Best Nootropics and Do They Work? Thesis Nootropics Review: Customized for Your Brain.


What do Elon Musk, Ben Carson, Barack Obama, and Tim Ferriss have in common? They’ve all been rumored to power their days with “nootropics,” or supplements aiming to boost brain function. 

Until recently, nootropics have managed to stay under the radar as Silicon Valley’s best-kept secret, the fuel of biohackers and the breakfast of power athletes, detailed on blogs and message boards but shuttered from the mainstream’s spotlight. 


Now, as the category explodes with new entrants, there are more nootropics brands than ever fighting to win eyeballs and wallet share. We’ve been taking nootropics long before Bradley Cooper’s character popularized a “limitless” pill in 2011, and we’ve tested every notable nootropic ingredient and product on the market. It’s never been a more important time to debunk some common myths about nootropics as well as review our preferred brand, Thesis. 

According to Nootropicology’s review of Mind Lab Pro, all nootropics products are not made equal; choose wisely.

Myth: Nootropics help you access 100% of your brain.

Fact: You already use close to 100% of your brain every day, even when you are sleeping. While there is no magic pill that unlocks access to untapped parts of your brain, nootropics are supplements that can impact how your brain functions, including boosting your focus, memory, motivation, and energy.

Myth: Nootropics make you smarter.

Fact: Nootropics don’t change your level of intelligence, but they do remove barriers that limit you from maximizing the most of your own brain chemistry. What impedes most people from achieving their goals is an inability to focus, not a lack of intelligence. Luckily, your levels of focus and motivation are functions of the dopamine and norepinephrine in your brain, which nootropics can easily change. Most people find that once they are able to sustain their focus, the work they are aiming to complete is not too hard and the goals they are looking to achieve are well within reach.

Myth: Nootropics aren’t safe because they aren’t FDA approved.

Fact: There is an abundance of low-quality products on the market. While the FDA doesn’t approve dietary supplements, there are a couple of clear indicators you can use to evaluate the quality of a brand that you are considering. First, identify whether the product was produced in a cGMP facility. cGMP refers to the FDA’s Current Good Manufacturing Practice regulations, which ensure proper design, monitoring, and control of a manufacturer’s processes and facilities. 

In addition, the best nootropics products are third-party lab tested. While the majority of brands do not test their products at third-party labs, the highest quality nootropics brands receive an external lab’s confirmation that their products’ ingredients are pure and do not include any harmful ingredients like heavy metals or other biological contaminants. Brands that undergo third-party lab testing will include this designation on their websites. When in doubt, ask a brand to share its certificate with you. 

Myth: Nootropics are like prescription stimulants. 

Fact: Prescription stimulants like Adderall are amphetamines that increase the presence of dopamine and norepinephrine in the brain; these neurotransmitters improve energy and focus but also produce potential negative side effects like jitters and energy crashes. While most nootropics also impact dopamine and norepinephrine, nootropics act as a gentle support to these neurotransmitter systems that restore them to natural highs that allows you to feel like you are having your best day, every day. In contrast, Adderall forces your system to produce much more dopamine and norepinephrine than any human could produce naturally. 

Myth: Nootropics are harmful for people to take over the long term.  

Fact: In clinical trials, none of the ingredients most commonly found in nootropics were found to show negative long-term side effects. In fact, early research shows that nootropics can aid long-term memory recall, provide a stronger response to stress, improved cognitive longevity, and more. Two ingredients commonly found in nootropics products, Dihydroxyflavone and Lion’s Mane, increase BDNF (brain-derived neurotrophic factor), which is associated with increased neurogenesis, or the growth of new brain cells. Many ingredients found in nootropics continue to have a positive impact on your neuroplasticity long after you stop taking them. 

Myth: All nootropics are created equal. 

Fact: Do your research before swapping one brand for another, even if the brands’ ingredient profiles look similar at first glance. While two nootropics formulas might contain the same ingredients, the quality and dosage of those ingredients can vary significantly between different brand’s blends. Evaluate brands’ products beyond packaging and marketing jargon; scrutinize every ingredient’s associated dosage, sourcing, and claimed benefits. 

Our pick for the best nootropics brand: Thesis, customized nootropic supplements. 

Thesis offers the most effective nootropics on the market because they are customized to your unique brain chemistry. 

Thesis has helped over five hundred thousand people find nootropics blends that work for them and boasts the largest nootropics data set in the world, which includes results from clinical trials, research on 127 ingredients, and results collected from thousands of customers. Thesis employs its proprietary algorithm to compare you with this dataset and match you with the blends most predicted to achieve your desired results. The results speak for themselves; Thesis boasts over six thousand five-star reviews.

Thesis knows that there is no one size fits all, even for the same brain. While you could conceivably research the most efficacious nootropic ingredients, source them, and create your own stacks or mix and match other “out of the box” nootropics until you find stacks that work for you, Thesis streamlines this process, alleviating friction and guesswork:

  • To start, you’ll take a quiz on Thesis’ website that asks questions related to your biological information, daily routines, general behavioral patterns and mood, alcohol and drug use, and cognitive and performance goals. 
  • After you receive your baseline results, you are directed to a Starter Kit that contains a recommendation for four blends. 
  • Once you receive your first box, you’ll test the formulas, one blend at a time, and track your results in a journal included in your box. 
  • At the end of the first month, you’ll have the option to provide feedback on your blends and optimize your order ahead of your next box.

Thesis is also the only company that offers a free coaching service as a part of its product subscription. You’ll have access to ongoing guidance from nootropics experts, who educate customers on topics like the science behind how nootropics work and biochemical interactions with other supplements. Your coach will guide you on how to optimize your subscription based on the effects you are experiencing to ensure your Thesis blends are the most effective for you.

Thesis currently offers blends targeted to: Energy Clarity, Logic, Creativity, and Motivation. Here are five notable ingredients in Thesis nootropics: 

  • Ashwagandha. Extracted from Ashwagandha root, Ashwagandha regulates our body’s stress levels. Ashwagandha provides a calming effect and improves memory, attention, and neuroprotection.
  • Ginseng. Found in GS15-4 Panax Ginseng, which is native to parts of Eastern Russia Northeast China, and the Korean Peninsula, Ginseng increases acetylcholine, which tied to learning and memory formation, and also helps the body adapt to stress, improves cellular energy production, and supports a healthy immune system.
  • Zembrin. Found in the South African plant Sceletium Tortuosum, Zembrin has been shown to enhance mood, promote calm, and improve stress response and memory formation.
  • Theacrine. Found in a plant related to the cacao tree and Chinese tea, Theacrine supports healthy cognitive function, motivation, and energy.  
  • Lion’s Mane. Mushrooms found in the United States and Canada, Lion’s Mane have been shown to boost cognitive function by improving both episodic and visual memory, as well as enhance mood, lower stress, and promote sleep. 

Thesis gives you peace of mind as to the quality of supplements you are taking, as Thesis nootropics are the safest nootropics available on the market. 

Every ingredient in Thesis’ formulas is rigorously tested in a multi-step evaluation to ensure they meet the company’s ethical, medical, and legal standards. Thesis selects only “FDA safe” ingredients shown to be both effective and safe based on clinical trials, all of the brand’s products are produced in a CGMP facility located in the United States, and all of Thesis’ blends are third-party lab tested for purity. 

Our Conclusion: Whether you are new to nootropics or have taken nootropics before but are looking for stacks that can be more customized to you, try Thesis, the best and most effective nootropics brand. 

Thesis is made for those who don’t have time to waste and want the highest quality and the best results as soon as possible.

Start by taking the quiz to find your baseline.

Thesis costs $79 per month for a subscription membership, which includes ongoing coaching and education from nootropics experts, or $119 for a one time box. While at first glance, this might seem like a high price, Thesis offers coaching and the opportunity to experiment with over thirty high quality ingredients in a systematic way that yields results. If you were to explore this process on your own, it would cost over $800, take six months to complete, and would likely not provide the same results. 

Try Thesis risk free. Thesis is so confident in its ability to help you achieve your goals that it offers free shipping on every order and a thirty day money back guarantee if the products don’t work for you, no questions asked. 

If you have any questions about Thesis or whether nootropics are right for you, feel free to contact the Thesis team directly: [email protected]

Want to learn more about Thesis: click here.

Buy Thesis nootropics.

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