How To Detect Antibodies With ELISA

Updated on April 28, 2020

In any type of medical testing, it’s imperative that the proper testing result is received. This is true across the board. However, it is truer than ever with the current coronavirus pandemic. 

As testing has lagged in many states, no one is fully sure of the extent that the coronavirus has spread through American society at this point. Different models from medical experts are presenting projections of varying percentages and no one can confirm if one model is more correct than another.

As multiple states moved towards reopening their economies, and the doors to many of their business, governors are desperate to know how many people in their state have been infected with the coronavirus already. 

This is where ELISA can come to help.

How ELISA Works

ELISA is a complex medical detection system that excels at detecting false positives.

With the need for antibody tests becoming increasingly important, governments all across the world are attempting to produce antibody tests that will detect if a person has had past exposure to the coronavirus. Unfortunately, many tests at this point are being debunked as ineffective. Some tests are presenting a large number of false positives while other tests are showing false negatives- even though a person was confirmed to have coronavirus when they were actively infected with it. 

ELISA’s system can troubleshoot some common problems that are known to arise in antibody tests. This ability would help improve upon the design of the current antibody tests that scientists are actively working on. 

ELISA can also process how sensitive a test is and process how specific a person’s antibodies need to be to fit with properly working coronavirus tests. Not every person will produce the exact same amount of antibodies for the coronavirus even after they’ve been infected, so ELISA can help determine the range for future antibody tests. 

ELISA Can Improve Antibody Testing

Further than simply tweaking the existing antibody tests, ELISA can also help determine which antibody or antigen systems are necessary within an individual for a test. 

For any virus, not just the coronavirus, ELISA can assist in determining this through an intricate optimization process to ensure that quality control is being met. This becomes especially important when a large number of tests are being produced rapidly at one time. Although antibody tests can always be tweaked slightly at a later date, if thousands of them are produced at one time with the same system, if they are not as perfect as possible, this can be disastrous for the company or government buying them.

For this reason, ELISA also excels at checking on the stability of antibody tests. With ELISA, problems can be detected within antibody tests before they’re used. ELISA can also determine a test’s shelf life to ensure that its accuracy does not begin to break down over time. 

ELISA has experience in chemistry, biochemistry, and molecular biology. If you’re someone who is currently working on producing antibody tests, get in touch!

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The Editorial Team at Healthcare Business Today is made up of skilled healthcare writers and experts, led by our managing editor, Daniel Casciato, who has over 25 years of experience in healthcare writing. Since 1998, we have produced compelling and informative content for numerous publications, establishing ourselves as a trusted resource for health and wellness information. We offer readers access to fresh health, medicine, science, and technology developments and the latest in patient news, emphasizing how these developments affect our lives.