Genetics and AFib: Understanding the Link

Updated on May 16, 2023

Atrial fibrillation (AFib) is a typical heart rhythm condition that affects millions of people in the U.S.A., as per the Centers for Disease Control and Prevention. It happens when the heart’s upper chambers beat irregularly, which can lead to blood clots, stroke, and heart failure. While there are numerous factors that may be the reason for the development of AFib, genetics plays a significant role.

In this article, we will explore how genetics can affect the development of AFib.

Understanding Genetics and AFib

AFib has been linked to several genetic mutations that can increase a person’s risk of developing the condition. In particular, mutations in genes that control the electrical signaling in the heart can cause irregular heartbeats and increase the likelihood of AFib. Some of these genetic mutations are inherited from a person’s parents, while others occur spontaneously. Additionally, certain genetic factors may make it more difficult for the body to respond to medications used to treat AFib, which can further complicate the condition.

Many people with AFib have a family history of the condition, indicating a strong genetic component. Several genes have been identified that increase the risk of developing AFib. One of these genes is KCNH2, which codes for a protein that plays a key role in the electrical signaling of the heart. Mutations in KCNH2 can lead to an abnormal heartbeat and increase the risk of AFib.

Another gene that has been linked to AFib is SCN5A, which also plays a role in the electrical signaling of the heart. Mutations in SCN5A can lead to an irregular heartbeat and increase the risk of AFib. Other genes that have been associated with AFib include PITX2, which regulates the development of the heart, and NPPA, which codes for a hormone that contributes to the regulation of blood pressure and the maintenance of fluid balance.

For people with AFib, finding the right medication and dosage is challenging, especially if genetic factors are complicating the condition. However, medications such as Eliquis 2.5 mg tablets effectively manage the symptoms of AFib and reduce the risk of stroke. By inhibiting the formation of blood clots, Eliquis helps prevent strokes in people with AFib.

The Role of Medications in AFib Treatment

AFib is a chronic condition that requires lifelong treatment. Among the most frequent and effective ways to manage AFib is through medication. Medications like Eliquis 2.5 mg tablet help prevent blood clots, reducing the risk of stroke and other complications. Eliquis is an anticoagulant medication that prevents clots from forming in the blood. It is one of the most commonly prescribed medications for people with AFib.

In addition to anticoagulants like Eliquis, other medications may be used to manage the symptoms of AFib. For example, rate control medications can help slow down the heart rate, reducing the risk of complications. Beta-blockers, calcium channel blockers, and digoxin are all examples of rate control medications that may be prescribed for people with AFib.

However, as mentioned earlier, some genetic factors can affect a person’s response to medication. In some cases, a higher dosage or a different medication may be needed to effectively manage the condition. People with AFib must collaborate closely with their healthcare provider to find the right medication and dosage to manage their condition.

While medications are an important part of AFib treatment, lifestyle changes can also play a role. Maintaining a healthy weight, getting regular exercise, and avoiding alcohol and caffeine can all help manage AFib symptoms. It is also important to manage other health conditions, such as high blood pressure and diabetes, which can increase the risk of AFib.

Ordering Medications from Canadian Pharmacies

One of AFib patients’ major struggles is finding safe and affordable medications. In the U.S.A., medications are prohibitively expensive, and many insurance plans do not cover the full cost of medications like Eliquis. This makes it difficult for you as a diabetic patient to afford the medications you need to manage your condition.

An online Canadian pharmacy provides a safe and affordable option for people who need medications like Eliquis 2.5 mg tablet to manage their AFib. In Canada, medications are priced much lower than in the U.S.A. due to government regulations. This means that people save a significant amount of money by buying Eliquis from Canada. Additionally, Canadian pharmacies are required to adhere to strict safety standards, ensuring that the medications they sell are safe and effective.

Ordering medications from Canadian pharmacies such as Polar Bear Meds is a simple process. People will order Eliquis 2.5 mg, Eliquis 5 mg tablets, and other medications online or by phone. Most Canadian pharmacies require a valid prescription from a healthcare provider, which can be submitted electronically. After the prescription is received, the medication is shipped directly to the person’s home.

It is important to note that while ordering medications from Canadian pharmacies is legal, only order from reputable and licensed pharmacies. The Canadian International Pharmacy Association (CIPA) is a reputable organization that provides a list of licensed online pharmacies that meet strict safety and quality standards.


AFib is a serious condition that is managed with the right medications. However, finding safe and affordable medications like Eliquis 2.5 mg tablet is challenging, especially for people in the U.S.A. Canadian pharmacies like Polar Bear Meds provide a great option for people who need these medications, as they provide lower prices and strict safety standards. It is important for AFib patients to coordinate closely with their healthcare providers to find the right medication and dosage to manage their condition.

With the help of safe and affordable medications, people with AFib live healthy and active life. And by ordering medications from Canadian pharmacies, they will save money and have peace of mind knowing that they are receiving safe and effective medications. So, if you are struggling to afford your medications for AFib, consider ordering them from a licensed Canadian pharmacy.

The Editorial Team at Healthcare Business Today is made up of skilled healthcare writers and experts, led by our managing editor, Daniel Casciato, who has over 25 years of experience in healthcare writing. Since 1998, we have produced compelling and informative content for numerous publications, establishing ourselves as a trusted resource for health and wellness information. We offer readers access to fresh health, medicine, science, and technology developments and the latest in patient news, emphasizing how these developments affect our lives.