Davos Alzheimer’s Collaborative To Showcase Groundbreaking Progress In Healthcare System Innovation And Inclusive Global Research At Aaic 2025

Teams Expand Research Across Africa; Advance Early Detection and Accurate Diagnosis, and Build Healthcare System Capacity

The Davos Alzheimer’s Collaborative (DAC), a worldwide initiative to prevent Alzheimer’s and improve brain health, will present significant new research and implementation outcomes at the 2025 Alzheimer’s Association International Conference (AAIC) in Toronto, Canada. These include data from multi-site healthcare system implementation projects and the expansion of DAC’s research footprint across five continents.

“We are on a path to the prevention of Alzheimer’s,” said Davos Alzheimer’s Collaborative Founding Chairman George Vradenburg. “Evidence is emerging that many Alzheimer’s cases can be delayed and even prevented, through risk-reducing action across the lifespan. The Davos Alzheimer’s Collaborative is helping translate that science into real-world impact by building the capacity of researchers, industry and health systems around the world to deliver early detection, diagnosis and treatment — accurately and equitably. The work we’re showcasing at AAIC is part of a broader shift: from isolated breakthroughs to scalable solutions.”

DAC-affiliated researchers and partners will present more than 30 posters and sessions during AAIC.

HEALTHCARE SYSTEM PREPAREDNESS

DAC’s Healthcare System Preparedness Program now includes 70+ program sites across 19 countries in 5 continents. At AAIC, DAC will spotlight emerging learnings and insights from its Accurate Diagnosis, Brain Health Navigator, and U.S. Early Detection Fellowship programs, showing how healthcare systems are translating research into sustainable clinical pathways using blood biomarkers, digital tools, and team-based models.

– Accurate Diagnosis sites in the U.S. (University of Kansas Medical Center), Germany (LMU Munich), and the Netherlands (Amsterdam UMC) will share real-world results from integrating blood-based biomarkers, cognitive screening, and decision support into memory clinics, primary care, and community-based models.

– U.S. Early Detection Fellowship sites in New York (NYC Health + Hospitals), New Jersey (Virtua Health), Pennsylvania (University of Pennsylvania Perelman School of Medicine), Indiana (Family Health Centers of Southern Indiana), and nationwide (CommonSpirit Health) are showing how DAC’s Early Detection Blueprint can catalyze large-scale adoption of cognitive screening and patient outreach—especially in underserved areas.

– DAC’s Brain Health Navigator pilot sites in Kentucky (Norton Neuroscience Institute), Ohio (University of Cincinnati Health), New Hampshire (Dartmouth Health), Michigan (Memorial Healthcare Institute for Neuroscience), and California (Sharp Reese-Stealy Medical Group and Keck Medicine of University of Southern California) are pioneering new clinical strategies to streamline the diagnostic journey, reduce time to treatment, and improve patient experience.

– In a July 29 featured Perspectives Session (Session #3-31-PER-B), DAC Advisor, Phyllis Barkman Ferrell, DrPH, MBA will join other thought leaders in the field to reflect on 25-years of Alzheimer’s disease research and progress.

– A July 30 Eisai Corporate Sponsored Symposium highlighting the DAC-SP Brain Health Navigator Program, “Brain Health Navigator: Ensuring Efficient and Effective Alzheimer’s Disease Diagnostic and Clinical Care Pathways,” will feature learnings from five leading U.S. healthcare system experts.

GLOBAL RESEARCH – WITH LANDMARK PROGRESS IN AFRICA

DAC’s Global Cohorts Program is comprised of 7 cohorts with over 40,000 participants on five continents. At AAIC, DAC will spotlight a major body of work from Kenya and Egypt. 

Posters include:

– The AD-Detect Kenya Project, a leading-edge effort to build predictive risk models in multilingual, community-based settings.

– Extensive research in Kenya, Egypt, Chile, Malaysia and India on digital speech and acoustic biomarkers, gender and poverty disparities, and public understanding of dementia.

– A multi-site South Korean push to identify and validate blood-based biomarkers for early dementia.

– Collaboration with the Egyptian Dementia Network on digital tool adaptation, biomarker registry creation, and environmental exposures (“neuroexposome”).

Featured research sessions will explore how to harmonize digital cognitive tools across cultures, while preserving local languages, customs, and realities of care delivery in LMICs.

DAC Global Cohorts will also hold a side event showcasing the progress and impact of the Global Cohorts Program, with a focus on learnings from community engagement, recruitment challenges, blood biomarker findings, digital cognitive assessments, and exposome research. DAC Global Cohorts Scholars from Egypt, Chile, and the Caribbean will present their work.

ABOUT THE DAVOS ALZHEIMER’S COLLABORATIVE

The Davos Alzheimer’s Collaborative (DAC) is a pioneering worldwide initiative to prevent Alzheimer’s disease, seeking to mirror the success of global efforts against infectious diseases. DAC is extending global research beyond its current focus on traditional Western European ethnic populations into the highly diversified populations of the Global South, where the vast majority of those with Alzheimer’s live. By introducing lower-cost screening and diagnostic tools as well as new treatment and prevention modalities in primary care and community health settings, DAC is driving implementation of health system solutions that are appropriate for worldwide application. DAC also promotes the vital importance of brain health throughout the lifespan by addressing cardiometabolic and lifestyle factors, especially in early and mid-life. Absent effective action at scale around the world, by 2050, more than 150 million families and half a billion people will be personally impacted by dementia, creating a social, financial, economic, and global security disaster of historic proportions. DAC was launched in Davos in 2021 by the World Economic Forum and the Global CEO Initiative on Alzheimer’s Disease. For more information, please visit: davosalzheimerscollaborative.org. 

DAC Healthcare System Program Posters at AAIC

Date	Site	DAC-SP Program	Abstract #	Poster #	Title	Authors(Bold indicates presenting author)
July 27	University of Kansas Medical Center	Accurate Diagnosis	99982	Sunday-539	Scaling Dementia Care Across a Health System: Integrating Biomarkers, Decision Support, and Collaborative Care Models	Jennifer Woodward, Timothy Ryan Smith, Jill Morris, Ryan Townley, Lindsey Gillen, Eric Vidoni, Dinseh Mudaranthakam, Adam Parks, Amanda Brunette, Michelle Niedens, Jaime Perales-Puchalt, Tina Lewandowski, Shellie Ellis, Emily Morrow, Janell Jones, Branden Comfort, Shelley Bhattacharya, Rachel Forcino, Taylor Bucy, Jeffrey Burns
July 28	Amsterdam UMC	Accurate Diagnosis	99978	Monday-536	Implementation of AD BBMs: Approach in Memory Clinics in the Netherlands	Floor Duits, Paula Vanneste, Niki Schoonenboom, Nicolaas Varwey, Salka Staekenborg, Astrid van Strien, Huga Aben, Argonde van Harten, Charlotte Teunissen
July 28	LMU Munich	Accurate Diagnosis	99980	Monday-537	The Community General Practitioner and General Specialist-based Cognitive Screening to Identify Early Decline in Seniors in Germany Study (COGSCREEN 2)	Robert Perneczky, Anna Hufnagel, Carolin Isabella Kurz, Paulina Tegethoff
July 30	National Institute of Geriatrics, National Institutes of Health, Mexico	Early Detection Flagship	99405	Wednesday-770	Barriers and facilitators for the implementation of an integrated evaluation for older adults including a digital cognitive tool in primary care settings in Mexico City	Mariana Lopez
July 30	Family Health Centers of Southern Indiana	U.S. Early Detection Fellowship	100452	Wednesday-711	A Federally Qualified Health Center pilot project for early screening and outreach in underserved areas in southern Indiana	Lori Harris
July 30	University of Pennsylvania Perelman School of Medicine	U.S. Early Detection Fellowship	100447	Wednesday-771	Building a cognitive and assessment pathway for primary care: The experience of one health care system	Kyra O’Brien, Wheeler Maxwell, Robert Burke, Joseph Teel, Jason Karlawish
July 30	Virtua Health and Rowan-Virtua School of Osteopathic Medicine	U.S. Early Detection Fellowship	100449	Wednesday-772	The DAC-SP Early Detection Blueprint: Catalyst for Sustainable Change in a Regional Health System	Elyse Perweiler, Kevin Overbeck, Mitchel King, David Libon, Maryann Graham, Samuel Weiner, Mary Campagnolo, Steven Santangelo
Virtual	CommonSpirit Health	U.S. Early Detection Fellowship	100455	Virtual	Scaling Early Detection for Mild Cognitive Impairment at CommonSpirit Health: Leveraging the DAC Blueprint and a Learning Health System Framework	Ankita Sagar, Gary Greensweig
Virtual	NYC Health + Hospitals/ Woodhull	U.S. Early Detection Fellowship	100457	Virtual	A Journey to the Early Detection of Alzheimer’s Disease in a Safety Net Hospital	Sakina Ouedraogo Tall, Jillian Diuguid-Gerber, Miesha Etheridge, Saima Amjal
July 30	Dartmouth Health	Brain Health Navigator	101261	Wednesday-775	Creating a sustainable brain health navigator model to improve the diagnostic journey for Alzheimer’s disease: the experience of one health care system in New Hampshire	Karen Blackmon, Dax Volle, Corie Crane
July 30	Memorial Healthcare Institute for Neuroscience	Brain Health Navigator	101272	Wednesday-776	Creating a sustainable brain health navigator model to improve the diagnostic journey for Alzheimer’s disease: the experience of one health care system in Michigan	Cara Leahy, Phincy Arangattu
July 30	Norton Neuroscience Institute	Brain Health Navigator	101274	Wednesday-777	Creating a sustainable brain health navigator model to improve the diagnostic journey for Alzheimer’s disease: the experience of one health care system in Kentucky	Gregory Cooper, Steven Patton, Deborah Lockridge, Stephanie Freeman
July 30	University of Cincinnati Health	Brain Health Navigator	101321	Wednesday-778	Creating a sustainable brain health navigator model to improve the diagnostic journey for Alzheimer’s disease: the experience of one health care system in Ohio	Rhonna Shatz, Katherine Schmidt, Anne Paul, Elizabeth Hente, Candace Burch
July 30	Keck Medicine of University of Southern California	Brain Health Navigator	101327	Wednesday-779	Creating a sustainable brain health navigator model to improve the diagnostic journey for Alzheimer’s disease: the experience of one health care system in California	Michael Young Lee, Soo Borson, Elizabeth Joe, Jennifer Marks, Bonnie Olson
Virtual	Sharp Reese-Stealy Medical Group	Brain Health Navigator	101320	Virtual	Creating a sustainable brain health navigator model to improve the diagnostic journey for Alzheimer’s disease: the experience of one health care system in California	John Clark, Andrea Snyder, Janet Appel

Perspectives Session Information:

Title: An Overview of the Consortia, non-profit groups and other organizations in the Alzheimer’s advocacy space over the past quarter century, part of session “Looking Backward and Looking Forward – A reflection on 25 years of Alzheimer’s Disease Research with Lessons for Future Progress”

Date, Time & Location: July 29, 2025 | 4:15-5:45 PM | Room 718, Metro Toronto Convention Centre

Presenter: Phyllis Barkman Ferrell, Davos Alzheimer’s Collaborative

Eisai Corporate Sponsored Brain Health Navigator Symposium: 

Title: Brain Health Navigator (BHN): Ensuring Efficient and Effective Alzheimer’s Disease Diagnostic and Clinical Care Pathways

Date, Time & Location: July 30, 2025 | 6:00 – 7:30 PM | The Westin Harbour Castle, Harbour Ballroom

Session Moderators & Speakers: 

• Karen Blackmon, Dartmouth Health
• Soo Borson, Keck Medicine of University of Southern California
• Greg Cooper, Norton Healthcare
• Phyllis Barkman Ferrell, Davos Alzheimer’s Collaborative (Moderator)
• Cara Leahy, Memorial Healthcare
• Rhonna Shatz, University of Cincinnati
• Donna Wilcock, Indiana University School of Medicine (Moderator)

DAC Global Cohorts Program Posters and Presentations at AAIC

DAC Program	Title	Authors(Bold indicates presenting author)
Global Cohorts	Pioneering Dementia Risk Prediction in Kenya: Insights from the AD-Detect Kenya Project	Chinedu T Udeh-Momoh
Global Cohorts	Understanding and Willingness to participate in Dementia Clinical trials in Kenya: An Ethnographic Study	Edna N Bosire, Lucy Wambui Kamau, Chinedu T Udeh-Momoh, Jasmit Shah, Karen Blackmon, Caroline Kalondu Kiio, Irene B Meier, Vaibhav Narayan, Olivera Nesic-Taylor, and Zul Merali
Global Cohorts	Blood-Based Clinical Markers for Early Dementia Detection: Insights from AD-DETECT-Cohort	Benard O Aliwa, Jasmit Shah, Olivera Nesic-Taylor, Samuel Nguku, Sheila Waa, Juzar Hooker, Dilraj Sokhi, Sylvia Mbugua, Litha Musili, Rachel W Maina, Harrison Kaleli, Levi A. Muyela, Anne Njoki Gitere, Anne Nyambura Njogu, Zul Merali, MD,8, Karen Blackmon, and Chinedu T Udeh-Momoh
Global Cohorts	Perceptions and attitudes on biospecimen sample collection for dementia research in Kenya	Lucy Wambui Kamau, Chinedu T Udeh-Momoh, Karen Blackmon, Caroline Kalondu Kiio, Jasmit Shah, Vaibhav Narayan, Irene B Meier, Olivera Nesic-Taylor, Zul Merali, and Edna N Bosire
Global Cohorts	Digital semantic fluency analysis detects dementia in multilingual Kenyan adults	Karen Blackmon, Levi A. Muyela, Johannes Tröger, Elisa Mallick, Nicklas Linz, Alexandra König, Anne Njoki Gitere, Anne Nyambura Njogu, Irene Meier, Vaibhav Narayan, Zul Merali, and Chinedu Udeh-Momoh
Global Cohorts	Gender Disparities in Multidimensional Poverty and Subjective Memory Complaints: Implications for Dementia Risk in Kenya	Cynthia Isabel Smith, Levi A. Muyela, Jasmit Shah, ALICE MORAA ONDIEKI, Raechel Kamau, Rachel W Maina, Anne Nyambura Njogu, Wambui Karanja, Karen Blackmon, Tamlyn J Watermeyer, and Chinedu Udeh-Momoh
Global Cohorts	Exploring Inflammation, Microbiota, Brain Resilience and Dementia in Kenyan Older Adults	Stanley Onyango, Benard O Aliwa, Benard Alaka, Jasmit Shah, Litha Musili, Harrison Kaleli, Cynthia Isabel Smith, Anne Nyambura Njogu, Catherine Bikeri Onyancha, Rachel W Maina, Omonigho M Bubu, Chiadi U. Onyike, Ozioma C. Okonkwo, Zul Merali, Mansoor Saleh, Shireen Sindi, Karen Blackmon, and Chinedu Udeh-Momoh
Global Cohorts	Demographic and Contextual Variability in the Underdiagnosis of Dementia-Related Cardiometabolic Risk Factors in African Populations	Chinedu T Udeh-Momoh, Jasmit Shah, Litha Musili, Harrison Kaleli, Cynthia Isabel Smith, Anne Nyambura Njogu, Catherine Bikeri Onyancha, Rachel W Maina, Omonigho M Bubu, Chiadi U. Onyike, Ozioma C. Okonkwo, Rufus O Akinyemi, Zul Merali, Mansoor Saleh, Adesola Ogunniyi, Karen Blackmon, and Hugh C Hendrie
Global Cohorts	Demographic and Contextual Variability in the Underdiagnosis of Dementia-Related Cardiometabolic Risk Factors in African Populations	Chinedu T Udeh-Momoh, Jasmit Shah, Litha Musili, Harrison Kaleli, Cynthia Isabel Smith, Anne Nyambura Njogu, Catherine Bikeri Onyancha, Rachel W Maina, Omonigho M Bubu, Chiadi U. Onyike, Ozioma C. Okonkwo, Rufus O Akinyemi, Zul Merali, Mansoor Saleh, Adesola Ogunniyi, Karen Blackmon, and Hugh C Hendrie
Global Cohorts	Measuring Safety: The Lifetime Sense of Safety Scale in Kenyan Adults	Anne Nyambura Njogu, Anne Njoki Gitere, Levi A. Muyela, Catherine Bikeri Onyancha, Lucy Wambui Kamau, Kendi Muchungi, Catherine Ajalo, Litha Musili, Jasmit Shah, Rachel W Maina, MS.c, Zul Merali, Chinedu Udeh-Momoh, and Karen Blackmon
Global Cohorts	A Systematic Review of Disparities in Alzheimer’s Diagnosis: The Overlooked Impact of Gender and Ethnoracial Diversity on Biomarker Expression	Cynthia Isabel Smith, Olisaemeka Ogbue, Nasra Gathoni, Karen Blackmon, Tamlyn J Watermeyer, Jasmit Shah, and Chinedu Udeh-Momoh
Global Cohorts	Digital speech biomarkers of cognitive functioning in multilingual Kenyan adults	Adolfo M Garcia, Levi A. Muyela, Alejandro Sosa Welford, Matías Caccia, Nicolás Pelella, Gonzalo Nicolás Pérez, Franco Javier Ferrante, Anne Njoki Gitere, Anne Nyambura Njogu, Erick Muhando, Olivera Nesic-Taylor, Vaibhav Narayan, Irene Meier, Zul Merali, Chinedu Udeh-Momoh, and Karen Blackmon
Global Cohorts	Fair Harmonization. How can we harmonize digital cognitive tools while also preserving local culture and context?	Chinedu Udeh-Momoh
Global Cohorts	The Frontal Assessment Battery in Older Multilingual Kenyan adults	Anne Gitere
Global Cohorts	Challenges and best practices for adopting and implementing digital cognitive assessments in LMICs	Alexandra König, Janna Herrmann, Brett Veitch, Johannes Tröger, Nicklas Linz, Karen Blackmon, Mohamed Salama, Rashmin Gandhi, Sandra Cortés, Javiera Leniz, Irene B. Meier, Vaibhav Narayan
Global Cohorts	E-HCAP, a validated version of the cognitive assessment tool adapted to the Egyptian cultural and educational settings	Mohamed Salama
Global Cohorts	The Neuroexposome: Adding Environmental Dimensions to Dementia Studies in Africa	Mohamed Salama
Global Cohorts	The Egyptian Dementia Network (EDN) registry: Towards discovering novel biomarkers of early dementia	Mohamed Salama