Nucynta (Tapentadol) is a novel, centrally acting analgesic with dual mechanisms of action. The drug was approved for medical use by FDA in 2008, while in 2009, it was classified as a Schedule II drug.
The extended-release form of Tapentadol (Nucynta ER) has been proven effective for constant, around-the-clock treatment of persistent or chronic pains that are not controlled by other medications.
In 2008, the FDA approved Tapentadol to treat all painful sensations arising from muscular disorder, muscle injury, or post-operative surgery. However, this approval is limited to short-term conditions.
|Drug Name||Nucynta (Tapentadol)|
|Tablet Strength||50mg, 100mg|
|Available Packages||50, 100, 200, 300, 500 pills|
|Payment Method||Visa, MasterCard, Bitcoin, Net banking|
|Shipment||Express Delivery Service|
|Where to Buy||Buy Tapentadol Online|
How Do Tapentadol works?
According to Riemsma, Rob, et al. “Systematic review of tapentadol in chronic severe pain.” opioid painkillers like Tapentadol not only provide relief from pain but also mimic the action of naturally occurring chemicals called endorphins.
Like our natural endorphins, Tapentadol is a synthetic opioid that works by blocking the transmission of pain signals sent along nerves from your body. To your brain & spinal cord—so even though you may go through that same source of pain, it will not be as intense or bothersome.
The drug enhances the activity of a neurotransmitter called noradrenaline in the brain. Neurotransmitters are chemical compounds, act as messengers between nerve cells. Its enhancing effect helps relieve or alleviate the pain.
Uses of Tapentadol-
Tapentadol is indicated for the management of moderate to severe pain. It is used as an alternative for whom non-opioid analgesics provide insufficient pain relief and when alternative treatment fails to provide relief. Nucynta oral tablets or extended-release tablets are used for treating severe neuropathic pain associated with diabetic neuropathy.
However, it poses a risk of addiction, misuse, and abuse leading to an overdose. Immediate-release tablets are used for managing acute pain. The medication works best if taken at the onset of pain, and it is not found effective if the pain level is severe. It should always be administered as per your prescription.
Dosage and Administration-
Immediate release: Schedule ll
Extended release: Schedule ll
Acute Moderate-to-Severe Pain:
Immediate-release tablet or oral solution:
50-100 mg PO q4-6hr PRN; not to exceed 700 mg on day 1 and 600 mg/day & subsequently.
- 50-250 mg PO q12hr PRN; not recommended to exceed 500 mg/day.
- Opioid-naive patients: 50 mg PO q12hr; titrated to optimal dosage as prescribed; not recommended to exceed 500 mg/day.
Dosage for Chronic Severe Pain:
Indicated for the management of pain severe enough to require daily, around-the-clock treatment for which alternative options are inadequate.
50-250 mg PO q12hr; not recommended to exceed 500 mg/day.
Opioid-naive patients: 50mg PO q12hr; titrated to optimal dosage as required; not recommended to exceed 500 mg/day.
Nucynta takes about 30 minutes to release its effect after the single dose consumption. It stays up to 20 hours depending upon biological factors such as age, gender, and medical history. In contrast, the sustained release effects last for up to twelve hours, differing from person to person.
The average recommended dose of Tapentadol IR is 600 mg and Tapentadol ER is 500 mg/day. Do not exceed or decrease any of the doses without your doctor’s concern. It may lead to fatal issues in your body.
How Much Does Nucynta IR Cost?
The cost of a Nucynta oral tablet with the strength of 50mg is about $812 for a supply of 100 tablets, depending upon the pharmacy you choose to purchase the medication. 30 tablets of Nucynta 50mg is $200. It is always recommended to buy the medicine from an authentic vendor or a legitimate pharmacy.
Safe Place to Buy Generic Nucynta?
The pain medication Tapentadol (Nucynta) is relatively new to the market. It was initially approved by FDA as an immediate release formulation, while the extended-release version was approved later. You buy Tapentadol online at a meager price and in a hassle-free manner, as you can get the medicine delivered to your home. Always make a note that one should only buy Tapentadol from verified pharmacies. The online pharmacies with a good reputation would be the best choice for buying the medicine.
Meet Abby, a passionate health product reviewer with years of experience in the field. Abby's love for health and wellness started at a young age, and she has made it her life mission to find the best products to help people achieve optimal health. She has a Bachelor's degree in Nutrition and Dietetics and has worked in various health institutions as a Nutritionist. Her expertise in the field has made her a trusted voice in the health community. She regularly writes product reviews and provides nutrition tips, and advice that helps her followers make informed decisions about their health. In her free time, Jane enjoys exploring new hiking trails and trying new recipes in her kitchen to support her healthy lifestyle.