Regenerative medicine (RM), or biologic therapy, is a rapidly emerging field for which there is considerable excitement and potential. There are numerous therapies that promise to modulate cellular activity of injured or surgically repaired tissue to produce a higher fidelity, more restorative form of healing than results from the current standard of care. Physicians and patients are often confused by the lack of clarity about the exact nature of these products, the mechanism by which they enhance healing, and in which injuries or clinical scenarios a particular biologic product can demonstrate benefit.
The primary objective of any regenerative therapy is to improve functional outcomes by enhancing the overall healing paradigm to produce higher quality repair at the injured region or surgical site. In the professional, collegiate, high school, or weekend athlete, RM products are used both as an intermediate intervention for inflammatory or non-catastrophic injuries or as adjuvant therapy to surgical reconstruction. In less invasive interventions, RM is intended to manage inflammation and/or drive enhanced healing of musculoskeletal tissues. In surgical indications, RM is expected to accelerate healing and decrease scar formation and adhesions, leading to better outcomes.
Orthopedic surgeons, professional team physicians, and sports medicine specialists widely use these products to support healing of extra-articular connective tissue pathology and for intra-articular conditions following meniscal repair and after ligamentous or cartilaginous reconstructive procedures. Significant interest is developing in the use of biologics in the non-operative management of acute and chronic soft tissue injuries and in the modulation of degenerative osteoarthritis. [Read more…] about Consensus on Regenerative Medicine in Orthopedics and Sports Medicine