Research will study genetic factors and tau-protein pathologies in progressive supranuclear palsy (PSP)
CurePSP, the foundation for prime of life neurodegeneration, has funded four grants at a total of more than $300,000 to investigators at universities in the U.S. and Germany for innovative studies in progressive supranuclear palsy (PSP).
PSP is an incurable disease that is part of a spectrum of “prime of life” neurodegenerative afflictions, so named because they most often onset during middle age. These diseases progress rapidly with serious movement, behavioral, emotional, and cognitive symptoms that are largely untreatable.
The studies will investigate genetic factors involved in PSP as well as the behavior of the tau protein, which aggregates into tangles and destroys brain tissue. The tau protein is also involved in Alzheimer’s disease and other neurodegenerative conditions.
The study by Dr. Edward A. Burton of the University of Pittsburgh will identify gene variants that increase or reduce the risk of developing PSP and seek to uncover the biochemical mechanisms involved in the disorder. [Read more…] about CurePSP Supports Four New Studies Through its Venture Grants Program